Browsing Experimentally Confirmed database

Result: Your query found 63 resistance gene(s) from the BacMet Experimentally Confirmed database

Gene_nameExperimentally Verified Resistance Gene InformationPredicted Resistance Gene Information
abeS
  • BacMet ID: BAC0002
  • Code for: Efflux
  • Family: Small multidrug resistance (SMR) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acinetobacter baumannii
  • Location: Chromosome
  • Compound: Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Chlorhexidine [class: Biguanides], Pyronin Y [class: Xanthene], Rhodamine 6G [class: Xanthene], Methyl Viologen [class: Paraquat], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Acridine Orange [class: Acridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid], Crystal Violet [class: Triarylmethane], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Cetylpyridinium Chloride (CPC) [class: Quaternary Ammonium Compounds (QACs)], Dequalinium [class: Quaternary Ammonium Compounds (QACs)]
  • Description: Disinfectant resistance protein abeS. It can confer resistance to antibiotics such as erythromycin, novomycin, amikacin, ciprofloxacin, norfloxacin, tetracycline, trimethoporin and dyes, QACs etc.
  • Length (amino acid): 109
  • Reference: Srinivasan et al. 2009; Pubmed- 19770280

  • Similar resistance genes in 'BacMet Predicted database'
    acrD/yffA
  • BacMet ID: BAC0008
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Acriflavine resistance protein D; participates in the efflux of aminoglycosides. It confers resistance to a variety of these substances.
  • Length (amino acid): 1037
  • Reference: Nishino et al. 2001; Pubmed- 11566977, Nakamura et al. 1979; Pubmed- 378962

  • Similar resistance genes in 'BacMet Predicted database'
    acrE/envC
  • BacMet ID: BAC0009
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Acriflavine [class: Acridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Methyl Viologen [class: Paraquat], Ethidium Bromide [class: Phenanthridine]
  • Description: Acriflavine resistance protein E; May affect specific membrane functions, such as septum formation during cell division, and cell membrane permeability. It can confer resistance to novomycin.
  • Length (amino acid): 385
  • Reference: Klein et al. 1991; Pubmed- 1720861, Ma et al. 1993; Pubmed- 8407802, Nishino et al. 2001; Pubmed- 11566977

  • Similar resistance genes in 'BacMet Predicted database'
    acrF/envD
  • BacMet ID: BAC0010
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Acriflavine [class: Acridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Methyl Viologen [class: Paraquat], Ethidium Bromide [class: Phenanthridine]
  • Description: Acriflavine resistance protein F; Involved in cell envelope formation. It is produced in extremely low amounts.
  • Length (amino acid): 1034
  • Reference: Klein et al. 1991; Pubmed- 1720861, Nishino et al. 2001; Pubmed- 11566977

  • Similar resistance genes in 'BacMet Predicted database'
    adeA
  • BacMet ID: BAC0471
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acinetobacter baumanni
  • Location: Chromosome
  • Compound: Pyronin Y [class: Xanthene], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Acriflavine [class: Acridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Sodium Deoxycholate (SDC) [class: Acid], Ethidium Bromide [class: Phenanthridine], Methyl Viologen [class: Paraquat], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Rhodamine 123 [class: Xanthene], Synergize [class: QAC-Glutaraldehyde], Wex-cide-128 [class: Phenyl]
  • Description: AdeA membrane fusion protein. Part of the AdeABC efflux system. Confers resistance to antibiotics such as aminoglycosides, beta-lactams, chloramphenicol, tetracycline, tigercycline, trimethoprim, fluoroquinolones and other antibacterial compounds such as dyes, diamidines, biguanides, QACs and anionic detergents.
  • Length (amino acid): 396
  • Reference: Rajamohan et al. 2010; Pubmed- 20008046, Magnet et al. 2001; Pubmed- 11709311

  • Similar resistance genes in 'BacMet Predicted database'
    adeB
  • BacMet ID: BAC0472
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acinetobacter baumanni
  • Location: Chromosome
  • Compound: Pyronin Y [class: Xanthene], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Acriflavine [class: Acridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Sodium Deoxycholate (SDC) [class: Acid], Ethidium Bromide [class: Phenanthridine], Methyl Viologen [class: Paraquat], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Rhodamine 123 [class: Xanthene], Synergise, Wex-cide-128.
  • Description: AdeB RND protein. Part of the AdeABC efflux system. Confers resistance to antibiotics such as aminoglycosides, beta-lactams, chloramphenicol, tetracycline, tigercycline, trimethoprim, fluoroquinolones and other antibacterial compounds such as dyes, diamidines, biguanides, QACs and anionic detergents.
  • Length (amino acid): 1035
  • Reference: Rajamohan et al. 2010; Pubmed- 20008046, Magnet et al. 2001; Pubmed- 11709311

  • Similar resistance genes in 'BacMet Predicted database'
    adeC
  • BacMet ID: BAC0473
  • Code for: Efflux
  • Family: RND Superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acinetobacter baumanni
  • Location: Chromosome
  • Compound: Pyronin Y [class: Xanthene], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Acriflavine [class: Acridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Sodium Deoxycholate (SDC) [class: Acid], Ethidium Bromide [class: Phenanthridine], Methyl Viologen [class: Paraquat], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Rhodamine 123 [class: Xanthene], Synergize [class: QAC-Glutaraldehyde], Wex-cide-128 [class: Phenyl]
  • Description: AdeC outer membrane protein. Part of the AdeABC efflux system. Confers resistance to antibiotics such as aminoglycosides, beta-lactams, chloramphenicol, tetracycline, tigercycline, trimethoprim, fluoroquinolones and other antibacterial compounds such as dyes, diamidines, biguanides, QACs and anionic detergents.
  • Length (amino acid): 465
  • Reference: Rajamohan et al. 2010; Pubmed- 20008046, Magnet et al. 2001; Pubmed- 11709311

  • Similar resistance genes in 'BacMet Predicted database'
    adeI
  • BacMet ID: BAC0017
  • Code for: efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acinetobacter baumannii (strain AB0057)
  • Location: Chromosome
  • Compound: Acridine Orange [class: Acridine], Safranin O [class: Azin], Pyronin Y [class: Xanthene], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Acriflavine [class: Acridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Crystal Violet [class: Triarylmethane], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamidine], Sodium Deoxycholate (SDC) [class: Acid], Ethidium Bromide [class: Phenanthridine], Methyl Viologen [class: Paraquat], Rhodamine 123 [class: Xanthene], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Synergize [class: QAC-Glutaraldehyde], Virkon S [class: Peroxysulfate], Wex-cide-128 [class: Phenyl]
  • Description: Part of AdeIJK MDR pump. Contributes to resistance to beta-lactams, chloramphenicol, tetracycline, erythromycin, lincosamides, fluoroquinolines, fusidic acid, tigecycline, novobiocin, rifampin, trimethoprim and dyes such as acridine, safranin, pyronin, and anionic detergents such as sodium dodecyl sulfate.
  • Length (amino acid): 416
  • Reference: Damier-Piolle et al. 2008; Pubmed- 18086852, Rajamohan et al. 2010; Pubmed- 20008046

  • Similar resistance genes in 'BacMet Predicted database'
    adeT1
  • BacMet ID: BAC0478
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acinetobacter baumanni AC0037
  • Location: Chromosome
  • Compound: Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Acriflavine [class: Acridine], Rhodamine 123 [class: Xanthene], Methyl Viologen [class: Paraquat], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Acridine Orange [class: Acridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid], Synergize [class: QAC-Glutaraldehyde], Wex-cide-128 [class: Phenyl]
  • Description: It can confer resistant to antibiotics such as chloramphenicol, novobiocin, gentamicin, kanamycin, nalidixic acid, tetracycline etc.
  • Length (amino acid): 304
  • Reference: Srinivasan et al. 2011; Pubmed- 21212056

  • Similar resistance genes in 'BacMet Predicted database'
    adeT2
  • BacMet ID: BAC0479
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acinetobacter baumanni
  • Location: Chromosome
  • Compound: Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Rhodamine 123 [class: Xanthene], Methyl Viologen [class: Paraquat], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Acridine Orange [class: Acridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid], Crystal Violet [class: Triarylmethane], Synergize [class: QAC-Glutaraldehyde], Wex-cide-128 [class: Phenyl]
  • Description: It can confer resistant to antibiotics such as chloramphenicol, novobiocin, gentamicin, kanamycin, nalidixic acid, ciprofloxacin, erythromycin etc.
  • Length (amino acid): 238
  • Reference: Srinivasan et al. 2011; Pubmed- 21212056

  • Similar resistance genes in 'BacMet Predicted database'
    amvA
  • BacMet ID: BAC0025
  • Code for: Efflux
  • Family: MFS superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acinetobacter baumannii
  • Location: Chromosome
  • Compound: Acriflavine [class: Acridine], Chlorhexidine [class: Biguanides], Methyl Viologen [class: Paraquat], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Sodium Deoxycholate (SDC) [class: Acid]
  • Description: MFS efflux pump, AmvA (AedF). Mediates drugs, dyes, detergents, antibiotic and disinfectant resistance
  • Length (amino acid): 492
  • Reference: Rajamohan et al. 2010; Pubmed- 20573661

  • Similar resistance genes in 'BacMet Predicted database'
    baeR
  • BacMet ID: BAC0039
  • Code for: Regulator
  • Family: Contains 1 response regulatory domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Zinc (Zn), Tungsten (W), Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD and probably the casABCDE-ygbT-ygbF operons. Overexpression of BaeR increases resistance to novobiocin and deoxycholate. BaeR upregulates the mdtABCD locus and acrD and thereby increases the resistance to deoxycholate, metals and antibiotics.
  • Length (amino acid): 240
  • Reference: Baranova et al. 2002; Pubmed- 12107134, Yamamoto et al. 2008; Pubmed- 17884222, Lee et al. 2005; Pubmed- 15659689, Leblanc et al 2011; Pubmed- 21515766

  • Similar resistance genes in 'BacMet Predicted database'
    baeR
  • BacMet ID: BAC0596
  • Code for: Regulator
  • Family: Contains 1 response regulatory domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Salmonella Typhimurium
  • Location: Chromosome
  • Compound: Copper (Cu), Zinc (Zn), Tungsten (W), Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Member of the two-component regulatory system BaeS/BaeR. Activates BaeR by phosphorylation which then activates the mdtABCD and probably the casABCDE-ygbT-ygbF operons.
  • Length (amino acid): 240
  • Reference: Nishino et al. 2007; Pubmed- 17933888, Appia-Ayme et al. 2011; Pubmed- 21886814

  • Similar resistance genes in 'BacMet Predicted database'
    baeS
  • BacMet ID: BAC0040
  • Code for: Regulator
  • Family: Contains 1 HAMP domain, 1 histidine kinase domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Zinc (Zn), Tungsten (W), Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Member of the two-component regulatory system BaeS/BaeR. Activates BaeR by phosphorylation which then activates the mdtABCD and probably the casABCDE-ygbT-ygbF operons.
  • Length (amino acid): 467
  • Reference: Baranova et al. 2002; Pubmed- 12107134, Yamamoto et al. 2008; Pubmed- 17884222, Lee et al. 2005; Pubmed- 15659689, Leblanc et al 2011; Pubmed- 21515766

  • Similar resistance genes in 'BacMet Predicted database'
    baeS
  • BacMet ID: BAC0597
  • Code for: Regulator
  • Family: Contains 1 HAMP domain, 1 histidine kinase domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Salmonella Typhimurium
  • Location: Chromosome
  • Compound: Copper (Cu), Zinc (Zn), Tungsten (W), Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Member of the two-component regulatory system BaeS/BaeR. Activates BaeR by phosphorylation which then activates the mdtABCD and probably the casABCDE-ygbT-ygbF operons.
  • Length (amino acid): 467
  • Reference: Nishino et al. 2007; Pubmed- 17933888, Appia-Ayme et al. 2011; Pubmed- 21886814

  • Similar resistance genes in 'BacMet Predicted database'
    bepC
  • BacMet ID: BAC0042
  • Code for: Efflux
  • Family: RND superfamily, OMP/TolC family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Brucella suis biovar 1 (strain 1330)
  • Location: Chromosome
  • Compound: Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Acriflavine [class: Acridine], Crystal Violet [class: Triarylmethane], Ethidium Bromide [class: Phenanthridine], Rhodamine 6G [class: Xanthene], Sodium Deoxycholate (SDC) [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate]
  • Description: Involved in the efflux of toxic and relatively hydrophobic compounds. Influences survival inside the host. Probably part of a tripartite efflux pump, which is composed of an outer membrane efflux protein, an inner membrane protein and a protein that expands the periplasmic space. It can form a tripartite pump with BepD and BepE or with BepF and BepG.
  • Length (amino acid): 456
  • Reference: Posada et al. 2007; Pubmed- 17088356

  • Similar resistance genes in 'BacMet Predicted database'
    bepD
  • BacMet ID: BAC0043
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Brucella suis biovar 1 (strain 1330)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid], Ethidium Bromide [class: Phenanthridine], Crystal Violet [class: Triarylmethane]
  • Description: Efflux pump periplasmic linker BepD. Resistance conferred by BepDE is dependent on BepC. Involved in resistance to several unrelated toxic compounds, such as dyes, detergents and antibiotics such as ampicillin, norfloxacin, ciprofloxacin, tetracycline, and doxycycline.
  • Length (amino acid): 397
  • Reference: Martin et al. 2009; Pubmed- 19201794

  • Similar resistance genes in 'BacMet Predicted database'
    bepE
  • BacMet ID: BAC0044
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Brucella suis biovar 1 (strain 1330)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid], Ethidium Bromide [class: Phenanthridine], Crystal Violet [class: Triarylmethane]
  • Description: Efflux pump membrane transporter BepE. Resistance conferred by BepDE is dependent on BepC. Involved in resistance to several unrelated toxic compounds, such as dyes, detergents and antibiotics.
  • Length (amino acid): 1051
  • Reference: Martin et al. 2009; Pubmed- 19201794

  • Similar resistance genes in 'BacMet Predicted database'
    bepF
  • BacMet ID: BAC0045
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Brucella suis biovar 1 (strain 1330)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate]
  • Description: Efflux pump periplasmic linker BepF; Contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE
  • Length (amino acid): 411
  • Reference: Martin et al. 2009; Pubmed- 19201794

  • Similar resistance genes in 'BacMet Predicted database'
    bepG
  • BacMet ID: BAC0046
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Brucella suis biovar 1 (strain 1330)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate]
  • Description: Efflux pump membrane transporter BepG; Contributes to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE.
  • Length (amino acid): 1074
  • Reference: Martin et al. 2009; Pubmed- 19201794

  • Similar resistance genes in 'BacMet Predicted database'
    cmeD
  • BacMet ID: BAC0615
  • Code for: Efflux
  • Family: RND superfamily, OMF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Campylobacter jejuni
  • Location: Chromosome
  • Compound: Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Triton X-100 [class: Polyethylene glycol], Tween 20 [class: Polyoxyethylene], Empigen [class: Amine betaine], Sodium Cholate [class: Acid], Sodium Glycocholate [class: Acid], Sodium Taurocholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Chenodeoxycholate [class: Acid]
  • Description: CmeD is the outer membrane protein.
  • Length (amino acid): 424
  • Reference: Akiba et al. 2006, Pubmed- 16303882

  • Similar resistance genes in 'BacMet Predicted database'
    cmeE
  • BacMet ID: BAC0616
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Campylobacter jejuni
  • Location: Chromosome
  • Compound: Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Triton X-100 [class: Polyethylene glycol], Tween 20 [class: Polyoxyethylene], Empigen [class: Amine betaine], Sodium Cholate [class: Acid], Sodium Glycocholate [class: Acid], Sodium Taurocholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Chenodeoxycholate [class: Acid]
  • Description: CmeE is a periplasmic fusion protein
  • Length (amino acid): 246
  • Reference: Akiba et al. 2006, Pubmed- 16303882

  • Similar resistance genes in 'BacMet Predicted database'
    cmeF
  • BacMet ID: BAC0069
  • Code for: Efflux
  • Family: RND superfamily; AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Campylobacter jejuni
  • Location: Chromosome
  • Compound: Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Triton X-100 [class: Polyethylene glycol], Tween 20 [class: Polyoxyethylene], Empigen [class: Amine betaine], Sodium Cholate [class: Acid], Sodium Glycocholate [class: Acid], Sodium Taurocholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Chenodeoxycholate [class: Acid]
  • Description: Integral membrane component of efflux system (Multidrug efflux system CmeDEF)
  • Length (amino acid): 1005
  • Reference: Akiba et al. 2006, Pubmed- 16303882

  • Similar resistance genes in 'BacMet Predicted database'
    emrK
  • BacMet ID: BAC0151
  • Code for: Efflux
  • Family: MFS superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Crystal Violet [class: Triarylmethane], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Sodium Deoxycholate (SDC) [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate]
  • Description: EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein; overexpression resistance to deoxycholate
  • Length (amino acid): 387
  • Reference: Tanabe et al. 1997; Pubmed- 12501312, Kato et al. 2000; Pubmed- 10923791

  • Similar resistance genes in 'BacMet Predicted database'
    evgA
  • BacMet ID: BAC0154
  • Code for: Regulator
  • Family: Contains 1 HTH luxR-type DNA-binding domain, Contains 1 response regulatory domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Only gram -ve, Escherichia coli (Strain K12)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Member of the two-component regulatory system EvgS/EvgA. Regulates the expression of emrKY operon and yfdX. Seems also to control expression of at least one other multidrug efflux operon.
  • Length (amino acid): 204
  • Reference: Kato et al. 2000; Pubmed- 10923791, Nishino et al. 2001; Pubmed- 11157960

  • Similar resistance genes in 'BacMet Predicted database'
    evgS
  • BacMet ID: BAC0155
  • Code for: Regulator
  • Family: Contains 1 histidine kinase domain, 1 response regulatory domain, 1 HPt domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Sensor protein EvgS; Member of the two-component regulatory system EvgS/EvgA. Phosphorylates EvgA via a four-step phosphorelay in response to environmental signals
  • Length (amino acid): 1197
  • Reference: Kato et al. 2000; Pubmed- 10923791, Nishino et al. 2001; Pubmed- 11157960

  • Similar resistance genes in 'BacMet Predicted database'
    hmrM
  • BacMet ID: BAC0189
  • Code for: Efflux
  • Family: MATE family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Haemophilus influenzae
  • Location: Chromosome
  • Compound: Acriflavine [class: Acridine], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamidine], Ethidium Bromide [class: Phenanthridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Sodium Deoxycholate (SDC) [class: Acid], Hoechst 33342 [class: Bisbenzimide]
  • Description: Multidrug efflux pump that functions as a Na+/drug antiporter. Confers resistance to norfloxacin, Acriflavine, doxorubicin, ethidium bromide, tetraphenylphosphonium chloride, daunomycin, berberine and sodium deoxycholate
  • Length (amino acid): 464
  • Reference: Xu et al. 2003; Pubmed- 14695443

  • Similar resistance genes in 'BacMet Predicted database'
    kexD
  • BacMet ID: BAC0492
  • Code for: Effflux
  • Family: Restriction Nodulation Division (RND) superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Klebsiella pneumoniae
  • Location: Chromosome
  • Compound: Rhodamine 6G [class: Xanthene], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid]
  • Description: KexD was shown to function with AcrAEc and TolC from E. coli and AcrAKp and KocC from K. pneumoniae, like AcrD from E. coli
  • Length (amino acid): 1038
  • Reference: Ogawa et al. 2012; Pubmed- 22391093

  • Similar resistance genes in 'BacMet Predicted database'
    kpnE
  • BacMet ID: BAC0476
  • Code for: Efflux
  • Family: Small multidrug resistance (SMR) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Klebsiella pneumoniae NTUH-K2044
  • Location: Chromosome
  • Compound: Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Triclosan [class: Phenolic compounds], Methyl Viologen [class: Paraquat], Hydrogen Peroxide (H2O2) [class: Peroxides]
  • Description: KpnEF is a EbrAB homolog. kpnEF is involved in oxidative stress tolerance, nitrosative stress tolerance, heat stress tolerance, osmotic stress toerance etc. in Klebsiella pneumoniae. It can confer resistance to antibiotics such as cefepime, ceftriaxone, colistin, erythromycin, rifamycin, tetracycline and streptomycin.
  • Length (amino acid): 120
  • Reference: Srinivasan et al. 2013; Pubmed- 23836167

  • Similar resistance genes in 'BacMet Predicted database'
    kpnF
  • BacMet ID: BAC0477
  • Code for: Efflux
  • Family: Small multidrug resistance (SMR) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Klebsiella pneumoniae NTUH-K2044
  • Location: Chromosome
  • Compound: Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Triclosan [class: Phenolic compounds], Methyl Viologen [class: Paraquat], Hydrogen Peroxide (H2O2) [class: Peroxides]
  • Description: KpnEF is a EbrAB homolog. kpnEF is involved in oxidative stress tolerance, nitrosative stress tolerance, heat stress tolerance, osmotic stress toerance etc. in Klebsiella pneumoniae. It can confer resistance to antibiotics such as cefepime, ceftriaxone, colistin, erythromycin, rifamycin, tetracycline and streptomycin
  • Length (amino acid): 109
  • Reference: Srinivasan et al. 2013; Pubmed- 23836167

  • Similar resistance genes in 'BacMet Predicted database'
    mdtA/yegM
  • BacMet ID: BAC0210
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Multidrug resistance protein MdtA; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate; MdtABC requires TolC for its function
  • Length (amino acid): 415
  • Reference: Baranova et al. 2002; Pubmed- 12107134,

  • Similar resistance genes in 'BacMet Predicted database'
    mdtB/yegN
  • BacMet ID: BAC0211
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid], Hydrochloric acid (HCl) [class: Acid]
  • Description: Multidrug resistance protein MdtB; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate. MdtABC requires TolC for its function.
  • Length (amino acid): 1040
  • Reference: Deininger et al. 2011; Pubmed- 21541325

  • Similar resistance genes in 'BacMet Predicted database'
    mdtC/yegO
  • BacMet ID: BAC0212
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Multidrug resistance protein MdtC; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate. MdABC requires TolC for its function.
  • Length (amino acid): 1025
  • Reference: Nishino et al. 2001; Pubmed- 11566977, Nagakubo et al. 2002; Pubmed- 12107133

  • Similar resistance genes in 'BacMet Predicted database'
    mdtE/yhiU
  • BacMet ID: BAC0213
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Crystal Violet [class: Triarylmethane], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Sodium Deoxycholate (SDC) [class: Acid], Rhodamine 6G [class: Xanthene], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)]
  • Description: Multidrug resistance protein MdtE; Part of a multidrug resistance efflux system (mdtEF-TolC) that confers resistance to compounds such as rhodamine 6G, erythromycin, doxorubicin, ethidium bromide, TPP, SDS, deoxycholate, crystal violet and benzylkonium. Part of a tripartite efflux system composed of MdtE, MdtF and TolC. It has a role in biofilm formation of E. coli K12.
  • Length (amino acid): 385
  • Reference: Masuda et al. 2002; Pubmed- 12399493

  • Similar resistance genes in 'BacMet Predicted database'
    mdtF/yhiV
  • BacMet ID: BAC0214
  • Code for: Efflux
  • Family: RND superfamily, AcrB/AcrD/AcrF family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Crystal Violet [class: Triarylmethane], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Sodium Deoxycholate (SDC) [class: Acid], Rhodamine 6G [class: Xanthene], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)]
  • Description: Multidrug resistance protein MdtF; Part of a multidrug resistance efflux system that confers resistance to compounds such as rhodamine 6G, erythromycin, doxorubicin, ethidium bromide, TPP, SDS, deoxycholate, crystal violet and benzylkonium. Part of a tripartite efflux system composed of MdtE, MdtF and TolC.
  • Length (amino acid): 1037
  • Reference: Masuda et al. 2002; Pubmed- 12399493

  • Similar resistance genes in 'BacMet Predicted database'
    mdtG/yceE
  • BacMet ID: BAC0215
  • Code for: Membrane Transporter
  • Family: MFS superfamily, DHA1 family, MdtG subfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Multidrug resistance protein MdtG; Confers resistance to fosfomycin and deoxycholate
  • Length (amino acid): 408
  • Reference: Nishino et al. 2001; Pubmed- 11566977

  • Similar resistance genes in 'BacMet Predicted database'
    mdtI/ydgE
  • BacMet ID: BAC0216
  • Code for: Enzyme
  • Family: SMR superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Spermidine [class: Polyamines]
  • Description: Spermidine export protein MdtI; Catalyzes the excretion of spermidine. Can also confer resistance to deoxycholate and SDS
  • Length (amino acid): 109
  • Reference: Nishino et al. 2001; Pubmed- 11566977, Higashi et al. 2008; Pubmed- 18039771

  • Similar resistance genes in 'BacMet Predicted database'
    mdtK/ydhE
  • BacMet ID: BAC0218
  • Code for: Efflux
  • Family: MATE family, MdtK subfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Sodium Deoxycholate (SDC) [class: Acid], Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Acriflavine [class: Acridine]
  • Description: Multidrug resistance protein MdtK; It functions as a Na+/drug antiporter. Confers resistance to many drugs such as fluoroquinolones (norfloxacin, ciprofloxacin, enoxacin), tetraphenylphosphonium ion (TPP), deoxycholate, doxorubicin, trimethoprim, chloramphenicol, fosfomycin, Acriflavine, ethidium bromide and benzylkonium
  • Length (amino acid): 457
  • Reference: Nishino et al. 2001; Pubmed- 11566977

  • Similar resistance genes in 'BacMet Predicted database'
    oxyRkp
  • BacMet ID: BAC0536
  • Code for: Regulator
  • Family: LysR-family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Klebsiella pneumoniae NTUH-K2044
  • Location: Chromosome
  • Compound: Hydrogen Peroxide (H2O2) [class: Peroxides], Sodium Deoxycholate (SDC) [class: Acid], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene], Ethidium Bromide [class: Phenanthridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate]
  • Description: Activator of hydrogen peroxide-inducible genes. It has contributory role towards varied stress tolerance in K. pneumoniae.
  • Length (amino acid): 305
  • Reference: Srinivasan et al. 2013; Pubmed- 23619002

  • Similar resistance genes in 'BacMet Predicted database'
    qacEdelta1
  • BacMet ID: BAC0323
  • Code for: Efflux
  • Family: Small multidrug resistance (SMR) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Both gram +ve and -ve , Staphylococcus aureus, E. faecalis, P .aeruginosa
  • Location: Plasmid Rms149, In786, R388-R151 hybrid , pOZ176 , pKM0509, R1033, pKLC102, pLQ1001
  • Compound: Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Chlorhexidine [class: Biguanides], Pyronin Y [class: Xanthene], Rhodamine 6G [class: Xanthene], Methyl Viologen [class: Paraquat], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], 4,6-diamidino-2-phenylindole (DAPI) [class: Diamindine], Acridine Orange [class: Acridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid], Crystal Violet [class: Triarylmethane], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Cetylpyridinium Chloride (CPC) [class: Quaternary Ammonium Compounds (QACs)], Dequalinium [class: Quaternary Ammonium Compounds (QACs)]
  • Description: Disinfectant resistance protein QacEdelta 1. It can confer resistance to antibiotics as well such as erythromycin, novomycin, amikacin, ciprofloxacin, norfloxacin, tetracycline, trimethoporin etc.
  • Length (amino acid): 115
  • Reference: Kazama et al. 1999; Pubmed- 10339831, Paulsen et al. 1993; Pubmed- 8494372

  • Similar resistance genes in 'BacMet Predicted database'
    tolC
  • BacMet ID: BAC0393
  • Code for: Efflux
  • Family: RND Superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Phenol [class: Phenolic compounds], Triclosan [class: Phenolic compounds], Sodium Deoxycholate (SDC) [class: Acid], Sodium Cholate [class: Acid], Sodium Taurodeoxycholate [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Proflavin [class: Acridine], Acriflavine [class: Acridine], Ethidium Bromide [class: Phenanthridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Rhodamine 6G [class: Xanthene], Tetraphenylarsonium (TPA) [class: Quaternary Ammonium Compounds (QACs)], Cetrimide (CTM) [class: Quaternary Ammonium Compounds (QACs)], Dequalinium [class: Quaternary Ammonium Compounds (QACs)], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Plumbagin [class: Naphthoquinone]
  • Description: Required for proper expression of outer membrane protein genes such as ompF, nmpC, protein 2, hemolysin, colicin V, or colicin E1. May be specialized for signal sequence independent, extracellular secretion in Gram-negative bacteria. Required for acrAB, mar efflux pumps to act as multidrug efflux pump.
  • Length (amino acid): 493
  • Reference: Hackett et al. 1983; Pubmed- 6312426, Fralick et al. 1996; Pubmed- 8824631, Sulavik et al. 2001; Pubmed- 11257026

  • Similar resistance genes in 'BacMet Predicted database'
    vceA
  • BacMet ID: BAC0418
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio cholerae
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Part of the The VceCAB multidrug (hydrophobic compounds including deoxycholate (DOC), antibiotics, such as chloramphenicol and nalidixic acid, and the proton motive force uncoupler, cyanide carbonyl m-chlorophenylhydrazone (CCCP)) resistance pump; Can function with outer membrane OprM, an OMF family member instead of VceC
  • Length (amino acid): 395
  • Reference: Colmer et al. 1998; Pubmed- 9466256

  • Similar resistance genes in 'BacMet Predicted database'
    vceB
  • BacMet ID: BAC0419
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio cholerae
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Part of the The VceCAB multidrug (hydrophobic compounds including deoxycholate (DOC), antibiotics, such as chloramphenicol and nalidixic acid, and the proton motive force uncoupler, cyanide carbonyl m-chlorophenylhydrazone (CCCP)) resistance pump; Can function with outer membrane OprM, an OMF family member instead of VceC
  • Length (amino acid): 511
  • Reference: Colmer et al. 1998; Pubmed- 9466256

  • Similar resistance genes in 'BacMet Predicted database'
    vceC
  • BacMet ID: BAC0420
  • Code for: Efflux
  • Family: RND superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Part of the The VceCAB multidrug (hydrophobic compounds including deoxycholate (DOC), antibiotics, such as chloramphenicol and nalidixic acid, and the proton motive force uncoupler, cyanide carbonyl m-chlorophenylhydrazone (CCCP)) resistance pump; Alpha-helical hairpin domain of Vibrio cholerae VceA play important roles in recognition/specificity/recruitment in the assembly of a functional, VceAB-OprM chimeric efflux pump
  • Length (amino acid): 484
  • Reference: Woolley et al. 2005; Pubmed- 16030246, Bai et al. 2010; Pubmed- 20206171

  • Similar resistance genes in 'BacMet Predicted database'
    vceR
  • BacMet ID: BAC0421
  • Code for: Regulator
  • Family: TetR (tetracycline resistance) family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
  • Location: Chromosome
  • Compound: Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Repressor of the vceCAB operon, VceR; VceR regulates the VceCAB drug efflux pump operon by alternating between mutually exclusive conformations that bind either drugs or promoter DNA
  • Length (amino acid): 200
  • Reference: Woolley et al. 2005; Pubmed- 16030246, Borges-Walmsley et al. 2005; Pubmed- 15890203

  • Similar resistance genes in 'BacMet Predicted database'
    vexH
  • BacMet ID: BAC0509
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio cholerae serotype O1
  • Location: Chromosome
  • Compound: Triton X-100 [class: Polyethylene glycol], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid]
  • Description: VexH contributes to antimicrobial resistance and exhibits broad substrate specificity. VexH is important for intestinal colonization and virulence factor production. V. cholerae RND efflux pumps (e.g. vexAB, vexCD etc.) have redundant functions, not only in antimicrobial resistance, but also in virulence factor production. RND efflux system contribute to V. cholerae pathogenesis in two ways. First, the RND efflux systems function to provide the bacterium with protection against antimicrobial compounds that are present in the host. Second, the RND efflux systems are required for efficient production of virulence factors. VexH can confer resistance to antibitics such as ampicillin and novobiocin.
  • Length (amino acid): 1036
  • Reference: Taylor et al. 2012; Pubmed- 22666485

  • Similar resistance genes in 'BacMet Predicted database'
    vmeA
  • BacMet ID: BAC0429
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus
  • Location: Chromosome
  • Compound: Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene], Crystal Violet [class: Triarylmethane], Ethidium Bromide [class: Phenanthridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Membrane fusion protein VmeA
  • Length (amino acid): 379
  • Reference: Matsuo et al. 2007; Pubmed- 18048926

  • Similar resistance genes in 'BacMet Predicted database'
    vmeB
  • BacMet ID: BAC0430
  • Code for: Efflux
  • Family: RND superfamily, MFP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus
  • Location: Chromosome
  • Compound: Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Acriflavine [class: Acridine], Rhodamine 6G [class: Xanthene], Crystal Violet [class: Triarylmethane], Ethidium Bromide [class: Phenanthridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Deoxycholate (SDC) [class: Acid]
  • Description: Inner membrane protein VmeB
  • Length (amino acid): 1053
  • Reference: Matsuo et al. 2007; Pubmed- 18048926

  • Similar resistance genes in 'BacMet Predicted database'
    vmeC
  • BacMet ID: BAC0510
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Glycocholate [class: Acid], Sodium Taurocholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Cholate [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Rhodamine 6G [class: Xanthene], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Hoechst 33342 [class: Bisbenzimide]
  • Description: VmeCD uses a outer memberane protein such as TolC in E. coli or TolC-like VpoC in V. parahaemolyticus to function properly but complexes with VpoC can extrude various antimicrobial agents more effectively than complexes with TolC.
  • Length (amino acid): 368
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeD
  • BacMet ID: BAC0511
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Glycocholate [class: Acid], Sodium Taurocholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Cholate [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Rhodamine 6G [class: Xanthene], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Ethidium Bromide [class: Phenanthridine], Acriflavine [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Hoechst 33342 [class: Bisbenzimide]
  • Description: VmeCD uses a outer memberane protein such as TolC in E. coli or TolC-like VpoC in V. parahaemolyticus to function properly but complexes with VpoC can extrude various antimicrobial agents more effectively than complexes with TolC.
  • Length (amino acid): 1040
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeE
  • BacMet ID: BAC0512
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Ethidium Bromide [class: Phenanthridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Glycocholate [class: Acid], Acriflavine [class: Acridine]
  • Description: VmeEF uses a outer memberane protein such as TolC in E. coli or TolC-like VpoC in V. parahaemolyticus to function properly but complexes with VpoC can extrude various antimicrobial agents more effectively than complexes with TolC.
  • Length (amino acid): 364
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeF
  • BacMet ID: BAC0513
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Ethidium Bromide [class: Phenanthridine], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Glycocholate [class: Acid], Acriflavine [class: Acridine]
  • Description: VmeEF uses a outer memberane protein such as TolC in E. coli or TolC-like VpoC in V. parahaemolyticus to function properly but complexes with VpoC can extrude various antimicrobial agents more effectively than complexes with TolC.
  • Length (amino acid): 1037
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeG
  • BacMet ID: BAC0517
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Glycocholate [class: Acid], Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides]
  • Description: Part of VexGHI efflux transporter.
  • Length (amino acid): 343
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeH
  • BacMet ID: BAC0518
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Glycocholate [class: Acid], Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides]
  • Description: Part of VexGHI efflux transporter.
  • Length (amino acid): 361
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeI
  • BacMet ID: BAC0519
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Glycocholate [class: Acid], Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides]
  • Description: Part of VexGHI efflux transporter.
  • Length (amino acid): 1033
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeP
  • BacMet ID: BAC0522
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Glycocholate [class: Acid]
  • Description: Part of the VexPQ efflux transpporter. VexPQ VexGHI uses a outer memberane protein such as TolC in E. coli or TolC-like VpoC in V. parahaemolyticus to function properly but complexes with VpoC can extrude various antimicrobial agents more effectively than complexes.
  • Length (amino acid): 380
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeQ
  • BacMet ID: BAC0523
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Glycocholate [class: Acid]
  • Description: Part of the VexPQ efflux transpporter. VexPQ VexGHI uses a outer memberane protein such as TolC in E. coli or TolC-like VpoC in V. parahaemolyticus to function properly but complexes with VpoC can extrude various antimicrobial agents more effectively than complexes.
  • Length (amino acid): 1046
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeT
  • BacMet ID: BAC0524
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Glycocholate [class: Acid], Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Acriflavine [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)]
  • Description: Part of the VexTUV efflux transporter.
  • Length (amino acid): 361
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeU
  • BacMet ID: BAC0525
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Glycocholate [class: Acid], Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Acriflavine [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)]
  • Description: Part of the VexTUV efflux transporter.
  • Length (amino acid): 353
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeV
  • BacMet ID: BAC0526
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Glycocholate [class: Acid], Ethidium Bromide [class: Phenanthridine], Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Acriflavine [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)]
  • Description: Part of the VexTUV efflux transporter.
  • Length (amino acid): 1019
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeY
  • BacMet ID: BAC0514
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Glycocholate [class: Acid], Sodium Taurocholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Cholate [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate]
  • Description: Part of the VexYZ efflux transporter. VmeYZ uses a outer memberane protein such as TolC in E. coli or TolC-like VpoC in V. parahaemolyticus to function properly but complexes with VpoC can extrude various antimicrobial agents more effectively than complexes with TolC.
  • Length (amino acid): 375
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vmeZ
  • BacMet ID: BAC0515
  • Code for: Efflux
  • Family: RND superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Sodium Glycocholate [class: Acid], Sodium Taurocholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Cholate [class: Acid], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate]
  • Description: Part of the VexYZ efflux transporter. VmeYZ uses a outer memberane protein such as TolC in E. coli or TolC-like VpoC in V. parahaemolyticus to function properly but complexes with VpoC can extrude various antimicrobial agents more effectively than complexes with TolC.
  • Length (amino acid): 1050
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'
    vpoC
  • BacMet ID: BAC0516
  • Code for: Efflux
  • Family: RND superfamily, OMP family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Vibrio parahaemolyticus RIMD2210633
  • Location: Chromosome
  • Compound: Benzylkonium Chloride (BAC) [class: Quaternary Ammonium Compounds (QACs)], Chlorhexidine [class: Biguanides], Ethidium Bromide [class: Phenanthridine], Rhodamine 6G [class: Xanthene], Acriflavine [class: Acridine], Tetraphenylphosphonium (TPP) [class: Quaternary Ammonium Compounds (QACs)], Hoechst 33342 [class: Bisbenzimide], Sodium Dodecyl Sulfate (SDS) [class: Organo-sulfate], Sodium Cholate [class: Acid], Sodium Deoxycholate (SDC) [class: Acid], Sodium Glycocholate [class: Acid]
  • Description: Homologue of E. coli TolC outer membrane protein, vpoC.
  • Length (amino acid): 442
  • Reference: Matsuo et al. 2013; Pubmed- 23894076

  • Similar resistance genes in 'BacMet Predicted database'

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